Separatists are NPCs, specifically, they are Separatists in the Republic Senate.
Silence of the Clones Edit
At the Senate, the bill to create an army for the Republic was easily defeated. When the bill for making a new moon for Naboo to replace the moon destroyed by the Trade Federation came up, some Separatists in the Senate asked if this couldn't be some evil plot to destroy them. Padme Amidala insisted that the moon would be a Peace Moon that the people of Naboo desperately needed. When one of the Separatists asked if the Moon would have any military applications, Padme began to contemplate outloud all the scientific ways this could be plausible, but was hastily interrupted by Chancellor Palpatine who quickly called for a vote, and the bill was passed.