The Missiles were NPCs, smart missiles so smart they could actually think and even talk. They were used by the Separatists against the Jedi during the kidnapping of Chancellor Palpatine.
Revelation of the Sith[]
An enemy ship launched 4 smart Missiles at the ships piloted by Obi-Wan and Anakin and R2-D2. These missiles were so smart they could not only continue to pursue their intended targets after they initially dodged them, but they could even talk. Obi-Wan tried to use Force Suggestion on the missiles, but the Force had no effect on them. He then tried to persuade them to go after an enemy dreadnought, but the missiles refused. Anakin tried to talk them out of hitting his and Obi-Wan's ships by pointing out that it would end the missiles' own existence, but the missiles believed in the motto: "Live fast and die young." The missiles liked Obi-Wan and Anakin enough that one of them offered them the chance to decide which part of their ship the missile would hit. Anakin asked the missile to target his left engine, and it agreed. He then asked another missile to target his right engine, and it agreed. He then went into a tight spin. The missiles targeting his engines were each so focused on the engine they agreed to target, that they spiraled into each other, destroying each other while leaving Anakin and R2's ship unharmed. The two remaining smart missiles claimed they wouldn't make that mistake as they targeted Obi-Wan's ship. Obi-Wan found some space flotsam from the battle and flew through it. The missiles hit the flotsam and exploded.